How Much Does Zoloft (Sertraline) Cost On The Street?

Medically Reviewed by Johnelle Smith, M.D.

Updated on August 18, 2025

Zoloft is not considered to be an addictive substance, and it is commonly prescribed. As of 2025, Zoloft pills are sold on the street for about $1 to $2 per pill.

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Zoloft (Sertraline) is a selective serotonin reuptake inhibitor (SSRI) medication commonly prescribed to treat depression, obsessive-compulsive disorder, and panic disorders. The street price of Zoloft fluctuates based on location, availability, and local drug laws, and may sell for approximately $2 per pill in 2025.

This medication is considered to be a safe long-term antidepressant with low addiction potential. Because the medication is not supposed to be an addictive substance and it is commonly prescribed, it may be easy to obtain for off-label abuse throughout the United States.

Learn more about the street price of prescription drugs

What Factors Can Affect The Price Of Zoloft On The Street?

Zoloft is not a controlled substance and doesn’t typically make people feel high or euphoric. However, it occasionally gets sold illegally when people can’t afford their prescriptions or want to avoid going to the doctor.

Factors affecting illicit Zoloft prices:

  • Location of Sale: urban areas with more mental health resources may have different pricing than rural areas with limited psychiatric care
  • Legal Access: Zoloft is widely prescribed and relatively easy to get from doctors, keeping street prices very low
  • Dosage: higher doses (100mg, 150mg) might cost slightly more than lower starting doses (25mg, 50mg)
  • Generic Availability: generic sertraline is much cheaper than brand-name Zoloft, affecting street market pricing
  • Competition: other antidepressants like Prozac or Lexapro available in the area can influence Zoloft prices
  • Medical Oversight: since it requires ongoing medical monitoring, some people buy it illegally to avoid doctor visits and therapy requirements

The illegal Zoloft market is extremely small because it has almost no recreational value and is easily accessible through legitimate medical channels. Street prices remain low since there’s an abundant legal supply and minimal demand from people who use it recreationally. Most people who buy Zoloft illegally are battling mental health issues and can’t access proper medical care.

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Street Cost Of Zoloft VS. Pharmacy Cost

Generic Zoloft (sertraline) is covered by most health insurance plans. The pharmacy cost for Zoloft may be low or entirely free, depending on your plan. The average retail price of the generic version of this medication is around $34, and the name-brand cost is around $432.

The street costs of Zoloft are higher compared to the minimal expenses to an individual who has obtained a prescription for the medication through their physician.

Browse our directory or reach out to the Substance Abuse and Mental Health Services Administration (SAMHSA) for more information about addiction recovery.

This page does not provide medical advice. See more

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