DMT, often called “the spirit molecule,” is a powerful psychedelic drug that exists naturally in tiny amounts in the human brain. It’s also the main ingredient in ayahuasca, a traditional plant medicine used in South American religious ceremonies. While DMT has been used for spiritual purposes for centuries, synthetic versions of this drug have become available.
Most people who use DMT smoke or vaporize it to feel its effects quickly. However, some people choose to snort synthetic DMT in its crystal powder form instead. This method of using DMT is dangerous and can cause serious harm to both your nose and your overall health.
Learn more about the dangers and effects of snorting other drugs.
What Is DMT?
DMT ( N, N-dimethyltryptamine) is commonly produced as an illegal synthetic compound in the United States. People take DMT recreationally or to feel a greater sense of spiritual awareness. By itself, DMT is quickly metabolized, and it is usually combined with an MAOI (MAO-inhibitor) to slow its breakdown.
Regardless of origin, whether from South America or elsewhere, DMT’s use as a hallucinogenic drug produces strong mind-altering experiences. The highs associated with DMT are reportedly stronger than those derived through the use of other hallucinogens, such as psilocybin (magic mushrooms) or LSD (acid).
Side Effects Of DMT
DMT does not create the same experiences for everyone. The drug’s purity, the quantity taken, a person’s mental health, and the person’s surroundings at the time the drug takes effect will influence outcomes.
DMT’s side effects include:
- altered senses of time
- altered sense of space
- profound experiences with perceived deities, aliens, or the universe
- out-of-body experiences
- auditory hallucinations
- visual hallucinations
- altered perceptions of reality
- altered perceptions of sounds
- altered visual perception
Freebase snorting DMT is reportedly very painful and is not considered a preferred method of ingestion because of the pain and because high doses are required to feel effects. Nasal ingestion of DMT is typically performed by mixing an MAOI with DMT powder into coconut cream, which is applied inside the nose.
DMT carries heavy side effects that may complicate existing health conditions. Typical side effects may include increased heart rate and blood pressure, agitation, chest pain, dizziness, and more. Side effects and “trip” outcomes are generally unpredictable, but even more so when DMT is taken with MDMA, cannabis, ketamine, or synthetic opioids like tramadol and fentanyl.
Side Effects Of Snorting DMT
DMT does not typically create physical dependence like strong opioids or benzodiazepines. However, it can result in serious short-term and long-term effects on the body. People with heart conditions are especially at risk when snorting DMT.
Possible side effects include:
- hypertension
- elevated heart rate
- high blood pressure
- nausea
- vomiting
- agitation
- rapid eye movements
- seizures
- dilated pupils
- respiratory arrest
- damaged voice
- damage to the nasal septum
- damage to the mucous membrane
- irritation
The combination of cardiovascular effects such as high blood pressure and elevated heart rate, along with the potential for seizures and breathing problems, can quickly become life-threatening. The damage to your nose and breathing passages from snorting DMT can also be permanent.
Long-Term Effects Of DMT Use
Besides the potential physical impact of having extended high blood pressure or heart rate, the major concern surrounding recreational DMT use involves altered mental status.
Mental Health Impact
Frequent use of hallucinogenic drugs like DMT can trigger a serious condition called hallucinogen persisting perception disorder, or HPPD. This disorder creates a psychotic state where people experience intense, unexpected flashbacks that interfere with their daily life and normal functioning. These flashbacks can happen at any time, even when the person hasn’t used the drug recently.
HPPD and other forms of persistent psychosis caused by hallucinogen use can also lead to mental health problems. People may experience disorganized thinking, making it hard to focus or make sense of their thoughts. They might develop paranoia, experience changes in how they see things around them, and have unpredictable mood swings as well.
Addiction To DMT
While DMT doesn’t cause physical addiction like other drugs, people can still develop a psychological dependence on it. Those who experience intense spiritual feelings or well-being from using DMT may find themselves wanting to recreate these experiences more often, leading them to use the drug repeatedly.
The signs of problem DMT drug abuse include:
- foregoing normal activities to get DMT
- sacrificing personal and professional relationships
- ignoring obligations
- craving DMT
- lying about drug use
- combining DMT with other drugs
- experiencing flashbacks or psychotic symptoms
- feeling out of touch
If you or a loved one are battling substance abuse, talk to an addiction specialist or your primary care provider. The Substance Abuse and Mental Health Services Administration (SAMHSA) can also provide more information, including local resources and rehab programs to help you get on the path to recovery.
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- Drug Enforcement Administration (DEA) — n,n-dimethyltryptamine (DMT)
https://www.deadiversion.usdoj.gov/drug_chem_info/dmt.pdf - National Institute on Drug Abuse (NIDA) — DrugFacts: Hallucinogens
https://nida.nih.gov/research-topics/psychedelic-dissociative-drugs
