Suboxone doses aren’t one-size-fits-all. Doctors adjust the amount based on several factors, like which opioids a person was using, how severe their withdrawal symptoms are, and how often they were using opioids before starting treatment. Most people start on a low dose and gradually work up to a target amount that keeps withdrawal symptoms under control.
Treatment typically follows a pattern over the first few days, with doses adjusted based on how a person responds. Once a stable, effective dose is found, it can be continued long-term under a doctor’s supervision.
Learn more about using Suboxone during medication-assisted treatment
Day-By-Day Doses Of Suboxone
If a person is just starting out on Suboxone treatment for an opioid use disorder, they’ll likely go through multiple stages of doses. Here are the states of Suboxone treatment as recommended by the manufacturer of the medication.
Day 1
On the first day of Suboxone treatment, patients start out at a dose of 2 mg/0.5 mg or 4 mg/1 mg buprenorphine and naloxone. The prescribing doctor can increase this in 2 or 4 mg increments of buprenorphine every two hours. The dose can reach up to 8 mg/2 mg on the first day depending on the symptoms of withdrawal exhibited.
Day 2
On the second day of Suboxone treatment, a person receiving the medication may remain at the same dose or continue to adjust as needed, During the second day, the prescribing doctor can administer up to 16 mg/4 mg in a single daily dose. Suboxone can be administered sublingually (under the tongue) or buccally (in the cheek). It’s recommended that Suboxone be administered sublingually on day two.
This is because the exposure to naloxone is somewhat higher when it’s administered buccally versus sublingually. Taking Suboxone sublingually will help to prevent sickness and precipitated withdrawal when increasing the dose on the second day.
Day 3 And Onwards
From the third day on, Suboxone should be increased or decreased in increments of 2 mg/0.5 mg or 4 mg/1 mg. The goal is to get the patient to a level of stability and suppress opioid withdrawal symptoms. The maintenance level of Suboxone (the level of medication that will be used daily from that point on) should be somewhere in the range of 4 mg/1 mg to 24 mg/6 mg as a single daily dose.
What Is The Target Dose Of Suboxone?
The recommended target dose of Suboxone is 16 mg/4 mg. For most people, this is the perfect amount of Suboxone to alleviate symptoms without having to take too much. Because Suboxone has a ceiling effect, doses above 24 mg/6 mg daily have no clinical advantages. Increasing the dose past this amount does not increase the effects of the medication.
Factors That Affect Doses Of Suboxone
For someone just beginning Suboxone treatment, there are multiple factors of consideration that prescribing doctors use to determine the best dosage for their patients.
The Level Of Withdrawal Symptoms Evident
The most straightforward indication that more or less Suboxone may be needed is by looking at the health and behavior of the individual. If a person is exhibiting signs of withdrawal, or certain symptoms do not subside, more medication is likely needed. But if a patient is healthy and feels normal, the dose is probably at a good level already.
The Type And Amount Of Opioid Abused
Different opioids of abuse will require different doses in Suboxone treatment. If a person has been abusing stronger opioids, they’ll likely have a higher tolerance built up to it. Similarly, a person who used opioid drugs more frequently than others may also have a higher tolerance built up in their system.
Both of these factors will require a higher level of Suboxone in order to alleviate symptoms of opioid withdrawal.
Home-Life May Affect Dosage
One factor that medical professionals will take into consideration for home administration of Suboxone is home life.
This includes things like:
- family stability
- an existing community of support
- life stressors
- level of stability
- financial or work situation
The reason a doctor may consider factors such as these is because a person may be more likely to abuse Suboxone if they don’t have any social support in place. This is why it can be helpful to receive Suboxone treatment in an addiction treatment center so there’s a guarantee of a safe, clinically supervised environment.
Get Suboxone Treatment For Opioid Use Disorder
If you or someone you care about is going through opioid withdrawal, Suboxone treatment can make the process safer and more manageable. It’s most effective when combined with medical supervision, ensuring doses are adjusted properly and any complications are caught early. Addiction treatment facilities can offer the support needed to get started on the path to recovery.
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- Suboxone.com—Patient Information for SUBOXONE® (buprenorphine and naloxone)
https://www.suboxone.com/ - Suboxone.com—Prescribing Information | SUBOXONE®
https://www.suboxone.com/pdfs/prescribing-information.pdf