Can You Get High On Zubsolv?

Medically Reviewed by Johnelle Smith, M.D. on December 28, 2021

Zubsolv is the name brand for an opioid addiction treatment medication that contains both buprenorphine and naloxone. When taken as prescribed, Zubsolv should not result in euphoria. Effects that may occur will be significantly lower than heroin or other opioids.

Can You Get High On Zubsolv?

Zubsolv is a sublingual tablet that is dissolved under the tongue. This prescription medication is classified as an opioid, but it does not result in the typical euphoric high like other opioids.

There have been reports, like those from the Substance Abuse and Mental Health Services Administration (SAMHSA), that some may experience feelings of well-being or positivity after taking Zubsolv.

However, after working with a medical professional, a person trying to manage an opioid use disorder (OUD) should not experience euphoria or feeling “high” after taking Zubsolv.

Read more about using Zubsolv in addiction treatment

Reasons Zubsolv Does Not Cause You To Feel High

One of the drugs in Zubsolv is buprenorphine. This medication does not completely bind to the opioid receptors in the brain, so it will not have the more extreme effects that heroin or morphine do.

Removing that high, while still providing enough medication to keep the person from going into full-blown withdrawal, is one of the ways Zubsolv is helping individuals with OUD.

Zubsolv also contains naloxone, which prevents or decreases potential abuse of Zubsolv.

Dissolving and injecting Zubsolv activates the naloxone, eliminating opioid effects quickly and rendering Zubsolv essentially useless.

Experiencing Euphoria While Taking Zubsolv

Taking Zubsolv as prescribed should not result in euphoria, so anyone taking Zubsolv as part of a medication-assisted treatment (MAT) program should see a medical professional.

A person who is not opioid-dependent may experience mild euphoria if they are abusing Zubsolv by taking it in higher doses or more often than prescribed.

Get Started On The Road To Recovery.

Get Confidential Help 24/7. Call Today!

(844) 616-3400

Zubsolv Protects Against The High Produced By Other Opioids

The opioid agonist, buprenorphine, does not fully attach to the opioid receptors. It cannot produce the same euphoric high as heroin, OxyContin, or other opioids.

Zubsolv is a long-acting opioid, so it takes effect at a much slower rate than other opioid drugs.

Finding Treatment For Zubsolv Abuse

Even though Zubsolv is included as one of the U.S. Food & Drug Administration’s (FDA) approved medications to treat OUD as part of a MAT program, it can be abused.

If you or a loved one are struggling with Zubsolv abuse, seeking treatment from an approved substance abuse recovery program can be helpful.

Contact our professionally trained staff today. We can help you find a recovery program that meets all your needs.

This page does not provide medical advice. See more

Addiction Resource aims to provide only the most current, accurate information in regards to addiction and addiction treatment, which means we only reference the most credible sources available.

These include peer-reviewed journals, government entities and academic institutions, and leaders in addiction healthcare and advocacy. Learn more about how we safeguard our content by viewing our editorial policy.

  • Was this Helpful?
  • YesNo
Medically Reviewed by
Johnelle Smith, M.D. on December 28, 2021
Let us walk you through the treatment process. We're here to help.
For 24/7 Treatment Help:
100% Free & Confidential. Call (844) 616-3400