Zubsolv is primarily used to decrease opioid cravings and ease withdrawal symptoms. The medication achieves this by blocking the effects of other opioid drugs.
It can be used as a short-term or long-term opioid addiction treatment medication regimen.
Zubsolv contains buprenorphine and naloxone — like the popular addiction medication, Suboxone. Zubsolv comes in sublingual tablets with higher bioavailability than other similar medications.
How Does Zubsolv Work To Block Opiates?
Because buprenorphine is an opioid partial agonist-antagonist, it will keep withdrawal symptoms from occurring in people that have recently stopped taking opioids. It will also work to block many other opioids from affecting a person.
The naloxone in Zubsolv prevents tampering with the drug and will cause severe withdrawal symptoms if the drug is snorted or injected.
Taken as directed, the naloxone in Zubsolv will not “kick off” buprenorphine or other opioids from receptor sites.
Zubsolv Prevents Opioid Withdrawal Symptoms
Symptoms of opioid withdrawals that Zubsolv helps to mitigate include:
- abdominal pain
- high blood pressure
- muscle aches
- excessive sweating
- runny nose
- rapid heartbeat
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How Long Does A Dose Of Zubsolv Block Opiates?
The buprenorphine in Zubsolv will typically stay in the body between 24 and 48 hours – depending on the quantity of drug taken. Typically, a person will take their dose of Zubsolv one time per day.
Naloxone, the part of Zubsolv that blocks the effects of opioids, will stay in the body’s system for up to 12 hours.
Appropriate dosages and medication administration will depend on a person’s level of opioid dependence, the type of opioid used, and progress in treatment.
Getting Help For An Opioid Addiction
Recovery from opioid addiction and dependence is a long road. With the help of professionals and, at times, pharmaceutical assistance, people with life-threatening opioid dependence can live fuller lives.
If you or somebody you know is struggling with opioids, it’s never too late to get help. Talk to one of our treatment specialists for information on the best rehab programs for your situation.
It is possible to get better. We’re here to help you find the best help for your unique needs.
Published on July 7, 2021
Addiction Resource aims to provide only the most current, accurate information in regards to addiction and addiction treatment, which means we only reference the most credible sources available.
These include peer-reviewed journals, government entities and academic institutions, and leaders in addiction healthcare and advocacy. Learn more about how we safeguard our content by viewing our editorial policy.
- Substance Abuse and Mental Health Services Administration (SAMHSA) — Buprenorphine
- Substance Abuse and Mental Health Services Administration (SAMHSA )— Naloxone
- U.S. National Library of Medicine: MedlinePlus—Buprenorphine Sublingual and Buccal
- Zubsolv—Frequently Asked Questions (FAQs)
- Zubsolv – Prescribing Information