How Does The Vivitrol Shot Work?

When using Vivitrol for addiction treatment, it helps to understand exactly how this medication supports recovery from both alcohol and opioid use disorder. Vivitrol is an extended-release, injectable form of naltrexone, used alongside substance use counseling and behavioral therapy as part of a broader treatment plan. It works by blocking opioid receptors in the brain, which can reduce the desire to drink alcohol or use opioids in the first place.

Because Vivitrol works the same way for both conditions, blocking the brain’s response to substances rather than replacing them, it’s become a widely used option for people working toward long-term sobriety from either alcohol or opioids.

How Vivitrol Works For Alcohol Use Disorder

Naltrexone, the primary ingredient in Vivitrol, is an opioid antagonist. Once it enters the brain, it binds to and blocks endorphin receptors associated with the “buzz” from alcohol.

When taken as directed, Vivitrol can help individuals with a history of alcohol dependence maintain their sobriety by reducing the desire to drink and by blocking its euphoric effects.

How Vivitrol Works For Opioid Use Disorder

Vivitrol is the only formulation of naltrexone that is FDA-approved as a medication-assisted treatment for opioid use disorder, also known as opioid addiction. As an opioid antagonist, Vivitrol is capable of blocking euphoria from opioids and can help reduce cravings to use opioids.

Unlike methadone and buprenorphine, two other medications used in the treatment of opioid addiction, Vivitrol is not an opioid. It is also non-addictive and doesn’t cause dependence.

How Is Vivitrol Taken?

Vivitrol is a drug that is administered by a healthcare professional once monthly by way of an injection into the gluteal muscle of the buttocks. Vivitrol shots can be given by a physician, nurse practitioner, physician’s assistant, or a pharmacist, as long as they are licensed to prescribe and administer medications.

Who Might Be A Good Candidate For Vivitrol?

Vivitrol tends to be a good fit for people who’ve already completed detox and are looking for a non-opioid option to help maintain their sobriety. Since it’s non-addictive and doesn’t cause physical dependence, it can be appealing to those who’d rather avoid medications like methadone or buprenorphine, even though those medications work well for many people too.

That said, Vivitrol isn’t the right choice for everyone. People who haven’t fully detoxed from opioids, or who may need opioid-based pain management in the near future, should talk to their doctor about whether Vivitrol fits their specific situation and treatment goals. A healthcare provider can help weigh these factors to determine the best path forward.