Xanax And Ativan | Dangers Of Mixing Alprazolam And Lorazepam

Xanax (alprazolam) and Ativan (lorazepam) are prescription benzodiazepines commonly used to treat symptoms of panic disorders, anxiety disorders, and insomnia. These short-acting drugs last between five to eight hours for a typical dose, and extended-release tablets (XR) can be felt for upwards of 12 hours. When abused, benzos like Xanax and Ativan may be combined with barbiturates for increased effect, or with opioids to ward off negative withdrawal symptoms from opioid dependence.

Serious drug interactions may occur when benzos are combined, used in higher doses for off-label treatment, and when combined with other CNS depressants like alcohol or barbiturates. Benzos can be abused through methods like crushing and snorting pills (insufflation), plugging, and orally. Snorting prescription drugs can increase the risk of overdose, especially when snorting extended-release benzos. When used as prescribed by a healthcare provider, Xanax and Ativan can produce uncomfortable side effects. Using these drugs together will only amplify negative effects.

Short-Term Side Effects Of Xanax And Ativan

Xanax and Ativan, two commonly prescribed benzodiazepines, are often used to treat anxiety, panic disorders, and insomnia. While these medications can be effective when taken as directed under medical supervision, they can also cause a range of uncomfortable short-term side effects.

Many people experience one or more of the following effects in the short-term:

• decreased blood pressure
• slow breathing
• headache
• sedation
• weakness
• amnesia
• vertigo
• confusion
• suicidal ideation
• drowsiness
• dizziness
• loss of motor skills
• memory and concentration problems
• mood swings
• slurred speech
• blurry vision
• dry mouth

It’s important to note that while these short-term side effects can be distressing, they typically subside as the body adjusts to the medication. However, if any of these symptoms persist or worsen, it’s crucial to consult with a healthcare professional. They may need to adjust the dosage or consider alternative treatment options. By staying informed and maintaining open communication with a medical provider, individuals can minimize the risk of adverse reactions.

Risks Of Polydrug Benzo Abuse

Misusing or abusing prescription benzos carries severe short-term and long-term risks. Drugs like Xanax, Ativan, and Valium can be highly addictive when used for an extended period of time.

Long-term benzo abuse symptoms may include:

• long-term memory loss
• heart issues
• depression
• suicidal idea
• hallucinations
• irritability
• trouble focusing
• memory impairment
• mania
• liver damage

Persistent polydrug benzo drug use, even when used for the treatment of anxiety disorders, may increase the risk of overdose symptoms and long-term negative mental health effects. Benzo abuse can also increase drug tolerance and create physical dependence where the body needs the drug to function “normally.” Xanax and Ativan dependence can cause withdrawal symptoms when a person stops using the drug, sometimes after even a short amount of time.

Fatal Overdose Risk With Alprazolam And Lorazepam Drug Use

When benzos are taken in excess or combined with other CNS depressants, a person is at a higher risk of fatal overdose due to combined depressant effects.

Some signs that a person may be experiencing an overdose include:

• coma
• respiratory depression (can lead to pneumonia and death)
• weak heartbeat
• low blood pressure
• confusion
• tremors
• weakness
• loss of coordination
• blurred vision and extreme dizziness
• lethargy
• slurred speech
• weak heartbeat
• hypnotic state

Overdoses can occur when a person uses multiple benzos at the same time, or with increased frequency or higher doses to achieve the same results. Because Ativan and Xanax are not frequently prescribed together (Xanax is not usually prescribed for children). The use of both drugs together may be the result of theft from family or friends, or from illegal drug purchases.

Addiction And Withdrawal Symptoms

Prolonged benzo use involving Xanax and Ativan can create chemical dependency. A supervised detox tapering off both drugs is the safest way to stop using benzos. If somebody that uses benzos regularly or intensely suddenly stops using the drug, withdrawals can begin within a day after not having the drug in the system.

Withdrawal symptoms may include:

• seizures
• irritability
• increased body temperature
• shakiness
• sweats
• erratic behavior
• anxiety
• insomnia
• agitation
• aggression
• hallucinations
• heart palpitations
• vomiting
• depression
• increased heart rate and blood pressure
• strong cravings

Depending on the frequency and intensity of drug use, symptoms of benzo withdrawal can last upwards of a couple of months. The most intense physical effects and cravings may last for a few days without the drugs. Side effects of Ativan and Xanax withdrawal can include symptoms that can be dangerous when unsupervised.

Treatment Options For Xanax And Ativan Abuse

Xanax and Ativan abuse can lead to severe physical and psychological dependence, making it challenging for individuals to quit on their own. Fortunately, there are several effective treatment options available for individuals facing Xanax and Ativan addiction.

Treatment options for Xanax and Ativan abuse include:

• Medical Detox: A supervised detox process that helps individuals safely manage withdrawal symptoms as they discontinue the use of Xanax or Ativan.
• Inpatient Rehabilitation: Intensive, residential treatment programs that provide 24/7 support and a structured environment for recovery.
• Outpatient Treatment: Less intensive than inpatient rehab, outpatient programs allow individuals to receive treatment while continuing to live at home and fulfill work or school obligations.
• Cognitive Behavioral Therapy (CBT): A form of psychotherapy that helps individuals identify and change negative thought patterns and behaviors associated with their substance abuse.
• Medication-Assisted Treatment (MAT): The use of FDA-approved medications, such as buspirone or gabapentin, in combination with therapy to help manage withdrawal symptoms and reduce cravings.
• Support Groups: Peer-led groups, such as Narcotics Anonymous (NA) or Benzodiazepine Recovery Support Group (BRSG), that provide a supportive community and promote ongoing recovery.
• Holistic Therapies: Complementary treatments, such as yoga, meditation, or art therapy, that can help reduce stress, improve mental well-being, and support overall recovery.

Recovery is a journey, and with the right support and resources, individuals can overcome their addiction and build a healthier, more fulfilling life. Browse our directory or reach out to the Substance Abuse and Mental Health Services Administration (SAMHSA) for more information about addiction recovery.

Written by the Addiction Resource Editorial Staff