What Is A Lethal Dose Of Restoril (Temazepam)?

Medically Reviewed by Johnelle Smith, M.D. on August 1, 2023

Restoril (temazepam) is a prescription medication used to treat the symptoms of insomnia. It can be lethal in extremely high doses.

What Is The Lethal Dose Of Restoril?

Restoril, known by its generic name as temazepam, is a benzodiazepine used to treat insomnia.

The lethal dose for Restoril is 1,963 milligrams per kilogram (mg/kg) in mice, 1,833 mg/kg in rats, and more than 2,400 mg/kg in rabbits.

The average adult dose of Restoril is 15 mg, but doses can range between 7.5 mg and 30 mg.

Learn more about the lethal doses of commonly abused drugs.

How A Lethal Dose Of Restoril Is Determined

Restoril is in a class of drugs called sedatives or hypnotics. Restoril is an effective medication in making the body fall asleep quicker and stay asleep longer.

Not everyone who takes Restoril abuses it, but the body can build up a tolerance to the medication, which can lead to an increase in the dose and chemical dependency.

If a person ingests a high volume of Restoril, the body can respond with symptoms like:

  • confusion
  • coma
  • reduced or absent reflexes
  • respiratory depression
  • hypotension
  • loss of consciousness
  • fainting

These symptoms can be treated and are not always fatal.

There have been fatal cases where only Restoril was present in the body, but overdoses most often involve other substances such as depressants, including alcohol.

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Mixing Restoril (Temazepam) With Opioids Can Have Lethal Consequences

The U.S. Food and Drug Administration (FDA) warns against combining Restoril and opioids.

Mixing Restoril and opioids can result in heavy sedation, respiratory depression, coma, and in some cases death.

Other potentially fatal combinations include muscle relaxers, alcohol, and other sleeping medicines.

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Medically Reviewed by
Johnelle Smith, M.D. on August 1, 2023
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