
Itchy skin is a common side effect of methadone use for opioid use disorder. People who take methadone on a regular basis may experience itchiness as a short-term side effect.
Although this side effect is common, severe itchiness is not. Severe side effects of methadone may indicate a bigger problem that can better be discussed with your doctor.
Learn more about the physical effects of methadone
What Causes Itchiness With Methadone?
Narcotics like methadone release histamine, a chemical compound in the body that is generally released in response to inflammatory and allergic reactions.
This release of histamine as a result of methadone use can cause mildly itchy skin, flushing, and sweating—all of which are common side effects of methadone. Severe itchiness is less common.
Severe itchiness after taking methadone may be a sign of:
- methadone allergy
- adverse reaction
Itchy skin from an allergic reaction to methadone may be accompanied by a rash or hives. If your skin becomes very red, itchy, or pale after taking methadone, contact your doctor immediately.
Is Itching From Methadone Dangerous?
Feeling itchy after taking methadone isn’t usually a major cause for concern. This is common, and the sensation may subside shortly.
A methadone allergy or adverse reaction to methadone, however, is worth discussing with your doctor. Together, you can both determine whether continuing to take methadone is right for you.
Call Today To Learn More About Methadone
Methadone is a medication that is commonly used for the treatment of opioid use disorder, in combination with behavioral therapy and drug abuse counseling.
For more information, call us today to learn more about methadone and to find methadone treatment options for yourself or a loved one at a treatment center near you.
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- Journal of Pain and Symptom Management — Opioid-Induced Itching: Morphine Sulfate and Hydromorphone Hydrochloride
https://www.jpsmjournal.com/article/S0885-3924(98)00115-8/fulltext - Substance Abuse and Mental Health Services Administration (SAMHSA) — Methadone
https://www.samhsa.gov/medication-assisted-treatment/medications-counseling-related-conditions/methadone - U.S. National Library of Medicine: MedlinePlus — Methadone
https://medlineplus.gov/druginfo/meds/a682134.html