What Is An Average Dose Of Naltrexone?

Medically Reviewed by Johnelle Smith, M.D. on March 17, 2022

Naltrexone is a medication-assisted treatment (MAT) option that can come in the form of a tablet or injectable solution. The dose prescribed for a person may vary based on the drug formulation and other personal factors.

What Is The Average Dose Of Naltrexone?

Naltrexone is a medication that comes in the form of a long-acting injection or tablet. The recommended dose of naltrexone varies according to the formulation it comes in.

When taken as directed, a recommended dose of naltrexone can help block the euphoric effects of alcohol and opioids, and help prevent cravings.

Learn more about the benefits of taking Naltrexone

Average Dose Of Naltrexone For Alcohol Use Disorder

Naltrexone can be prescribed for alcohol dependence, or alcohol use disorder. This medication may come in the form of a tablet or monthly injection.

The FDA-recommended dose of naltrexone for adults is 50 mg taken once daily, in tablet form.

Naltrexone tablets may come in the form of:

  • 50 mg tablets (Revia)
  • 100 mg tablets (Depade)

The extended-release injectable form of naltrexone (Vivitrol) is indicated for the treatment of alcohol use disorder. This is delivered once monthly in 380 mg doses.

Average Dose Of Naltrexone For Opioid Use Disorder

Only the long-acting injectable form of naltrexone (Vivitrol) is FDA-approved as a medication-assisted treatment for opioid use disorder.

The recommended dose of this extended-release formulation of naltrexone is 380 mg delivered intramuscularly every four weeks or once a month.

Naltrexone tablets (Revia, Depade, or generic) are not indicated for use as a treatment for heroin addiction or opiate addiction.

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Factors That Can Affect Your Prescribed Dose Of Naltrexone

Not all people prescribed naltrexone may be directed to take the same dosage amount.

Factors that can affect your prescribed dose:

  • history of liver damage
  • use of other medications
  • treatment setting

For maximum benefit, take naltrexone exactly as prescribed by your doctor or prescribing healthcare provider.

Find Naltrexone Treatment At A Rehab Center Near You

Naltrexone is one of several medications approved for the treatment of alcohol and opioid use disorder, both of which can be life-threatening conditions when left untreated.

If you’re looking for substance abuse treatment for yourself or a loved one, call us today to speak to a staff member about finding the right treatment program for you.

This page does not provide medical advice. See more

Addiction Resource aims to provide only the most current, accurate information in regards to addiction and addiction treatment, which means we only reference the most credible sources available.

These include peer-reviewed journals, government entities and academic institutions, and leaders in addiction healthcare and advocacy. Learn more about how we safeguard our content by viewing our editorial policy.

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Medically Reviewed by
Johnelle Smith, M.D. on March 17, 2022
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